Emergency services were called to Pentonville Road at around 8.30pm on Wednesday evening amid reports that persons had been struck by a London bus and had become entrapped.
A road closure has been put in place at Kings Cross Bridge and a rescue operation launched to free those involved.
Police Paramedics and Fire crews have all been scrambled to the incident.
A number of fire engines and Rescue support units have been mobilised to the scene.
A spokesman for the Met Police said: Police were called by the London Ambulance Service at 20:31hrs on Wednesday, 3 November to reports of a collision involving a bus and a cyclist on Pentonville Road, N1.
Officers and London’s Air Ambulance are in attendance.
The road is closed to traffic.
More to follow