The 50-year-old victim was found suffering a knife wound by police after being attacked at 8.20pm on Sunday in Ben Jonson Road, Stepney.
He was taken to hospital where his injury was declared not life-threatening.
Detectives believe the man may have been knifed during a suspected robbery.
A Met spokesman said: “Police were called to reports of a man with a stab injury on Ben Jonson Road in Tower Hamlets.
“Officers and the London Ambulance Service attended.
“The 50-year-old man was taken to hospital for treatment; his injury is not believed to be life-threatening.
“There have been no arrests and enquiries continue.”